Commercialisation of the Basella alba Leaf Extract as a Health Supplement - The Underlying Project of Bayan Token

Based on strong chemical and lab research, the Basella alba leaf extract is suggested for the treatment of hypercholesterolemia.

Hypercholesterolemia is the presence of high levels of cholesterol in the blood. An increased level of cholesterol can raise the risks of cardiovascular diseases and stroke.

According to a study by the World Health Organization, hypercholesterolemia is estimated to cause 2.6 million deaths annually and 29.7 million disability-adjusted life years (DALYs) in the global population. In Malaysia, coronary heart disease and stroke are two of the top causes of death. In a report published by WHO in May 2014, deaths caused by coronary heart disease reached 29,363 deaths and stroke deaths were 15,497 mortality.

Currently, statins are the only drug administered to patients as a prescribed medicine to treat cardiovascular diseases in the early stages for those with an elevated risk of cardiovascular disease. However, according to a study on the side effects of statin, though they are generally well tolerated, it can cause potentially severe side effects such as myopathy or rhabdomyolysis and polyneuropathy. Long-term consumption of statins causes severe adverse effects such as muscle and liver damage, rhabdomyolysis and acute renal failure. Additionally, a 2010 research review found that statins did not prevent mortality among people who were at risk of developing heart disease, only those who already have a history of heart diseases or heart attacks.

Due to these side effects, attention is now directed towards alternative medicines of plant origin.

The present study provides preliminary data that suggested the Basella alba leaf extract is capable of lowering cholesterol levels. In addition, the compounds of the leaf extract have been reported to possess beneficial effects in treating hypercholesterolemia and its related diseases. Studies in vivo models could give further insights into the effects and roles of B. alba as an alternative therapeutic agent in the prevention and management of hypercholesterolemia.

We believe that the development of a health supplement using the Basella alba leaf extract has the market potential to become a natural alternative to statins, not only in the domestic Malaysian market but also globally. In the future, we plan to establish lab facilities in order to develop the Basella alba compound as a drug that can be prescribed in medical facilities.

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