Again, grateful for your pleasantly written informative post, @homeydue. I didn't know Semmelweis; his story is very interesting but pathetic.
Catalina, like others included in your post (e.g. Vlad) is a very attractive historical protagonist, so much so that she has become a character in novels and fiction films. Among her lovers is said to have been a Venezuelan official, Francisco de Miranda. As you say, it happens with women who have assumed decisive roles that are subjected to falsehoods and manipulations.
In the case of Vlad the Impaler, I believe that he will be one of those who will always be accompanied by uncertainty and mystery; and it couldn't be any other way, since he is the historical figure who inspired the character of Dracula.
Greetings.