Artificial insemination methods to get pregnant
Getting pregnant is not always easy and accessible, and many women have to choose artificial insemination to get pregnant. Artificial insemination is the method by which sperm (sperm or donor sperm) is placed inside the reproductive system, uterus or cervix to allow fertilization of the fetus.
In case of infertility, the couple will be helped due to the following problems: artificial insemination:
In case of poor male infertility (low sperm count or poor motility means the inability of sperm during a long journey to the egg)
Weak endometriosis (endometriosis is a complication in which uterine-like tissues grow outside the uterus)
Infertility for unknown reasons
Unfavourable uterine mucosal wall
Ovulation problems
Sometimes using artificial insemination methods may not work for some couples, because the use of fertility drugs (to activate ovulation), as well as artificial insemination methods, increase your chances of success in fetal fertilization. For this reason, artificial insemination methods are successful for some people and not for others, because couples are in a different situation than each other.
Your doctor may suggest that fertility drugs be used before using artificial insemination methods, which are usually recommended near the time of the menstrual cycle. These drugs activate the ovaries to produce several mature eggs, while normally only one egg is released each month, which means that as the number of mature eggs increases, so does their chance of fertilization. Doctors usually do an ultrasound to find out the exact time of ovulation and to help you release the egg, they usually give you medicine 36-38 hours before artificial insemination. Once ovulation has occurred, continuing the artificial insemination process is a simple procedure. This is done in a doctor's office and is similar to a Pap smear. If you use your spouse's sperm, they will take a sperm sample from him or her that morning. Once the sperm sample is obtained, the sperm are washed to remove any possible restrictions on fertilization. If donor sperm is used, it is important to get it from a known donor organization.
The most common method of artificial insemination is the IUI method. This method uses a very small, flexible plastic tube called a "catheter"; In fact, the doctor will insert the concentrated sperm directly into the uterus through the cervix. Once this process is complete, you must stay in a supine position for 15 minutes, but then you can resume your normal life. It is usually recommended that you wait 14 days for a pregnancy test to be successful. Of course, the success rate of this method depends on the fertility problem, age and lifestyle of you and your spouse. Most couples who use artificial insemination have a five to ten per cent chance of getting pregnant in each cycle. If you take the recommended fertility drugs, your chances are likely to increase.
The positive thing is that you are pregnant, and the negative thing is that due to the side effects of ovulation stimulation, there is also the possibility of multiple pregnancies (although some couples consider it a reward for themselves). If you choose to use donor sperm, the other downside is that the fetus is not genetically related to your partner.
The role of HCG infertility and pregnancy
Human chorionic gonadotrophin (HCG) is a hormone produced during pregnancy. This hormone is produced by the placenta and feeds the egg after implantation in the uterus. HCG is first measured in the blood about 11 days after fertilization and in the urine between 12 and 14 days after fertilization. Levels of this hormone peak at 8 to 11 weeks and then decrease during pregnancy. HCG is the basis of laboratory tests (urine and blood) and is the best way to confirm pregnancy in early pregnancy.
Home pregnancy tests detect the hormone HCG in the urine and detect pregnancy. HCG is measured in international units IU / L (one global unit per litre). This means that if you have less than 5IU / L in your blood, you are not pregnant. But any amount above 25IU / L means you are pregnant.
After the last menstrual period (LMP), the amount of HCG hormone doubles on average every 30 hours, until it reaches 6500IU / L around the eighth week of pregnancy. After that, the rate of increase depends on the person and is about 60 to 70 The day after the last menstrual period (9th to 10th week of pregnancy) remains at its highest.HCG decreases slightly between the 12th and 16th week after the last menstrual period and remains constant until delivery, and one or two weeks after delivery HCG completely The body is cleansed.
The main function of this hormone is to prevent the uterine mucosa from clearing and the onset of menstruation or endometrium, which occurs normally in the menstrual cycle. In fact, after fertilization, the egg cell begins to multiply to form blastocytes. Trophoblasts and sensitized trophoblasts from around blastocytes. Sensitive trophoblast cells are the first cells to produce the hormone hCG. The hormone hCG, produced by sensitized trophoblast cells, acts on the corpus luteum and prevents it from breaking down. Progesterone produced by the corpus luteum acts on the cells of the uterine wall and prevents them from shedding, thus preparing the ground for implantation and the onset of pregnancy. On day 22, implantation is performed and with the formation of the placenta, the production of the hormones hCG and progesterone is performed by the placental cells.
Therefore, if the hormone HCG is not present in the pregnant body, the uterine tissue will begin to cleanse itself and the menstrual cycle will begin. Progesterone helps maintain thick uterine tissue for a healthy pregnancy. If the egg is fertilized, the tissue inside the uterus (endometrium) begins to enlarge and thicken until the fetus has the nutrients it needs to grow. HCG also plays a role in preventing the fetus's natural immune system from reacting as the placenta grows.
Excess HCG levels for weeks of gestation may indicate miscalculation of the fetus, single or even multiple. HCG levels lower than expected for weeks of pregnancy may indicate miscalculation, ectopic pregnancy, or the possibility of miscarriage. But sometimes, even though a full pregnancy is healthy, HCG levels are low.